next-generation deep sequencing Search Results


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ToolGen Incorporated next-generation sequencing-based targeted deep sequencing service
Next Generation Sequencing Based Targeted Deep Sequencing Service, supplied by ToolGen Incorporated, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Adaptive Biotechnologies Corp next-generation deep sequencing of the genomic dna of cd19+/cd5+/cd23- (b1a) splenocytes
SOX11 expression leads to clonal expansion of B cells. (A) <t>Deep</t> <t>sequencing</t> of the genomic <t>DNA</t> from B1a cells showing increased IgH gene clonality in Tg-SOX11 mice vs WT mice. (B) Decreased total productive rearrangements in the BCR repertoire of B1a cells of Tg-SOX11 mice vs WT mice showing a decrease in IgH gene diversity. (C) Frequency of the top 10 rearrangements compared with all other rearrangements of the IgH locus in B1a cells showing clonality in 2 Tg-SOX11 mice and oligoclonality in 2 Tg-SOX11 mice vs normal IgH diversity in the 2 WT mice. (D) Productive frequency of the top 100 IgH gene rearrangements shows loss of IgH diversity in all Tg-SOX11 mice (N = 4) as compared with WT mice (N = 2). In the histogram, each color represents a unique IgH clone, whereas the numerals represent the frequency of top clone in each mouse.
Next Generation Deep Sequencing Of The Genomic Dna Of Cd19+/Cd5+/Cd23 (B1a) Splenocytes, supplied by Adaptive Biotechnologies Corp, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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NextGen Sciences next-generation deep sequencing
Differences between ILS and ISS strains: Variant Breakdown. a Combined totals of variants that differ between the ILS and ISS strains. Synonymous mutations refer to a SNP(s) that alters the codon <t>sequence</t> but not the amino acid produced. Synonymous and non-synonymous mutations arise from the impact of a SNP on the underlying codon. Frameshifts are any indel not divisible by three, whereas deletions and insertions retain the reading frame. Variants are counted once per gene. b Combined totals of structural variations that differ between ILS and ISS strains. Losses and gains refer to changes in copy number, whereas a deletion is a complete loss/absence of a region. Chromosomal translocations refer to exchanges of large segments between chromosomes and inversions are reversals. c Distribution of structural variations by type, summarized by a sliding window approach (500 k windows with 100 k step size) (Color figure online)
Next Generation Deep Sequencing, supplied by NextGen Sciences, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Neurologische Klinik Selzer ultra-deep next-generation sequencing
Differences between ILS and ISS strains: Variant Breakdown. a Combined totals of variants that differ between the ILS and ISS strains. Synonymous mutations refer to a SNP(s) that alters the codon <t>sequence</t> but not the amino acid produced. Synonymous and non-synonymous mutations arise from the impact of a SNP on the underlying codon. Frameshifts are any indel not divisible by three, whereas deletions and insertions retain the reading frame. Variants are counted once per gene. b Combined totals of structural variations that differ between ILS and ISS strains. Losses and gains refer to changes in copy number, whereas a deletion is a complete loss/absence of a region. Chromosomal translocations refer to exchanges of large segments between chromosomes and inversions are reversals. c Distribution of structural variations by type, summarized by a sliding window approach (500 k windows with 100 k step size) (Color figure online)
Ultra Deep Next Generation Sequencing, supplied by Neurologische Klinik Selzer, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Cellecta Inc deep next-generation sequencing of the barcode cassette
Differences between ILS and ISS strains: Variant Breakdown. a Combined totals of variants that differ between the ILS and ISS strains. Synonymous mutations refer to a SNP(s) that alters the codon <t>sequence</t> but not the amino acid produced. Synonymous and non-synonymous mutations arise from the impact of a SNP on the underlying codon. Frameshifts are any indel not divisible by three, whereas deletions and insertions retain the reading frame. Variants are counted once per gene. b Combined totals of structural variations that differ between ILS and ISS strains. Losses and gains refer to changes in copy number, whereas a deletion is a complete loss/absence of a region. Chromosomal translocations refer to exchanges of large segments between chromosomes and inversions are reversals. c Distribution of structural variations by type, summarized by a sliding window approach (500 k windows with 100 k step size) (Color figure online)
Deep Next Generation Sequencing Of The Barcode Cassette, supplied by Cellecta Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Vela Diagnostics ultra-deep next-generation plasma hiv sequencing sentosa
Differences between ILS and ISS strains: Variant Breakdown. a Combined totals of variants that differ between the ILS and ISS strains. Synonymous mutations refer to a SNP(s) that alters the codon <t>sequence</t> but not the amino acid produced. Synonymous and non-synonymous mutations arise from the impact of a SNP on the underlying codon. Frameshifts are any indel not divisible by three, whereas deletions and insertions retain the reading frame. Variants are counted once per gene. b Combined totals of structural variations that differ between ILS and ISS strains. Losses and gains refer to changes in copy number, whereas a deletion is a complete loss/absence of a region. Chromosomal translocations refer to exchanges of large segments between chromosomes and inversions are reversals. c Distribution of structural variations by type, summarized by a sliding window approach (500 k windows with 100 k step size) (Color figure online)
Ultra Deep Next Generation Plasma Hiv Sequencing Sentosa, supplied by Vela Diagnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/ultra-deep next-generation plasma hiv sequencing sentosa/product/Vela Diagnostics
Average 90 stars, based on 1 article reviews
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SOX11 expression leads to clonal expansion of B cells. (A) Deep sequencing of the genomic DNA from B1a cells showing increased IgH gene clonality in Tg-SOX11 mice vs WT mice. (B) Decreased total productive rearrangements in the BCR repertoire of B1a cells of Tg-SOX11 mice vs WT mice showing a decrease in IgH gene diversity. (C) Frequency of the top 10 rearrangements compared with all other rearrangements of the IgH locus in B1a cells showing clonality in 2 Tg-SOX11 mice and oligoclonality in 2 Tg-SOX11 mice vs normal IgH diversity in the 2 WT mice. (D) Productive frequency of the top 100 IgH gene rearrangements shows loss of IgH diversity in all Tg-SOX11 mice (N = 4) as compared with WT mice (N = 2). In the histogram, each color represents a unique IgH clone, whereas the numerals represent the frequency of top clone in each mouse.

Journal: Blood

Article Title: SOX11 augments BCR signaling to drive MCL-like tumor development

doi: 10.1182/blood-2018-02-832535

Figure Lengend Snippet: SOX11 expression leads to clonal expansion of B cells. (A) Deep sequencing of the genomic DNA from B1a cells showing increased IgH gene clonality in Tg-SOX11 mice vs WT mice. (B) Decreased total productive rearrangements in the BCR repertoire of B1a cells of Tg-SOX11 mice vs WT mice showing a decrease in IgH gene diversity. (C) Frequency of the top 10 rearrangements compared with all other rearrangements of the IgH locus in B1a cells showing clonality in 2 Tg-SOX11 mice and oligoclonality in 2 Tg-SOX11 mice vs normal IgH diversity in the 2 WT mice. (D) Productive frequency of the top 100 IgH gene rearrangements shows loss of IgH diversity in all Tg-SOX11 mice (N = 4) as compared with WT mice (N = 2). In the histogram, each color represents a unique IgH clone, whereas the numerals represent the frequency of top clone in each mouse.

Article Snippet: We conducted next-generation deep sequencing of the genomic DNA of CD19 + /CD5 + /CD23 − (B1a) splenocytes to study their IgH gene repertoire (Adaptive Biotechnologies).

Techniques: Expressing, Sequencing

Differences between ILS and ISS strains: Variant Breakdown. a Combined totals of variants that differ between the ILS and ISS strains. Synonymous mutations refer to a SNP(s) that alters the codon sequence but not the amino acid produced. Synonymous and non-synonymous mutations arise from the impact of a SNP on the underlying codon. Frameshifts are any indel not divisible by three, whereas deletions and insertions retain the reading frame. Variants are counted once per gene. b Combined totals of structural variations that differ between ILS and ISS strains. Losses and gains refer to changes in copy number, whereas a deletion is a complete loss/absence of a region. Chromosomal translocations refer to exchanges of large segments between chromosomes and inversions are reversals. c Distribution of structural variations by type, summarized by a sliding window approach (500 k windows with 100 k step size) (Color figure online)

Journal: Mammalian Genome

Article Title: Genome characterization of the selected long- and short-sleep mouse lines

doi: 10.1007/s00335-016-9663-6

Figure Lengend Snippet: Differences between ILS and ISS strains: Variant Breakdown. a Combined totals of variants that differ between the ILS and ISS strains. Synonymous mutations refer to a SNP(s) that alters the codon sequence but not the amino acid produced. Synonymous and non-synonymous mutations arise from the impact of a SNP on the underlying codon. Frameshifts are any indel not divisible by three, whereas deletions and insertions retain the reading frame. Variants are counted once per gene. b Combined totals of structural variations that differ between ILS and ISS strains. Losses and gains refer to changes in copy number, whereas a deletion is a complete loss/absence of a region. Chromosomal translocations refer to exchanges of large segments between chromosomes and inversions are reversals. c Distribution of structural variations by type, summarized by a sliding window approach (500 k windows with 100 k step size) (Color figure online)

Article Snippet: However, technological and analytical advances, including high-throughput gene expression analysis and “Next-Generation” deep sequencing technologies (NextGen), are providing an unprecedented opportunity to examine the molecular basis of QTLs (Harrison ).

Techniques: Variant Assay, Sequencing, Produced